In 2018 the Therapeutic Goods Administration's Complaints Resolution Panel upheld a complaint about ads by this company on the grounds that they breached advertising codes. The ads were subsequently withdrawn.

In December 2016 Chemist Warehouse was ordered to back-pay more than $3.5 million for mandatory online training its workers did in their own time. Some 5976 employees, making up almost two-thirds of the retail pharmacy chain's workforce, have been paid back an average of about $600 for the training following an extensive Fair Work Ombudsman audit.

This company has been criticised for offensive advertising. In 2015 and 2020 Ad Standards upheld complaints about ads by this company on the grounds that they breached advertising codes. The ads were subsequently discontinued or modified.

This company has social responsibility claims on its website including community support and a statement on Caring for Our Environment.

Human Rights Law Centre's 2022 report, "Broken Promises: Two years of corporate reporting under Australia's Modern Slavery Act", examines statements submitted to the Government's Modern Slavery Register by 92 companies sourcing from four sectors with known risks of modern slavery: garments from China, rubber gloves from Malaysia, seafood from Thailand and fresh produce from Australia. Modern slavery statements are analysed to see if they comply with the mandatory reporting requirements, identify or disclose obvious modern slavery risks, and demonstrate effective actions to address risks. This company's modern slavery disclosure statement received a rating in the 31-40% range. The average score was 44% and the highest score was 89%.

According to data released by the Australian Tax Office in Jan 2022, this company was one of many local and foreign-based companies that paid no tax in Australia in 2019-20. Please note however that companies pay income tax on profits, not revenue (total income). While some companies use tax havens and loopholes to avoid paying their fair share of tax in Australia, other companies that paid no tax have perfectly legitimate reasons.